Week 15 DFS Defense Picks: Top Plays for FanDuel & Draft Kings Main Slate
In football, as in life, sometimes it’s the unsung heroes who make all the difference. Sure, quarterbacks get the MVPs, and wide receivers grab the highlights, but when it comes to DFS lineups, defenses can be the secret sauce that turns your $5 entry into a small fortune. So, here we are in Week 15, where playoff pushes are real and every snap matters. Let’s talk defenses—the guys who take the ball away, make quarterbacks miserable, and stack fantasy points like pancakes at an all-you-can-eat breakfast.
NFL DFS Week 15 Defense Picks
1. Dallas Cowboys ($3,700 FanDuel; $2,800 DraftKings)
What We Know: Dallas will face the Panthers, a team led by rookie QB Bryce Young. Young has thrown a league-high 11 interceptions, and Carolina’s offensive line is struggling to protect him.
What the Numbers Say: Carolina’s offense has the worst adjusted net yards per pass attempt (ANY/A) in the league. Dallas has exploited teams with similar inefficiencies, making this a high-ceiling play.
The Dallas Cowboys defense is a top DFS play in Week 14 due to their elite pass rush led by Micah Parsons, which creates frequent sack opportunities and forced fumbles. Their aggressive style, featuring playmakers like Trevon Diggs, leads to turnovers and potential defensive touchdowns—key for DFS scoring. The Cowboys excel against both the pass and the run, forcing offenses into predictable situations that increase their chances for big plays. With a favorable matchup and consistent high-floor performances, Dallas provides explosive potential while offering great value, allowing you to balance your budget and still secure top-tier defensive production.
NFL DFS Week 15 Defense Picks
2. Baltimore Ravens ($5,000 FanDuel; $3,900 DraftKings)
What We Know: The Ravens face the Giants, likely starting rookie QB Tommy DeVito. Baltimore’s opportunistic defense thrives against inexperienced signal-callers.
What the Numbers Say: The Giants have the worst offensive DVOA in the league. DeVito’s inexperience and Baltimore’s blitz-heavy scheme make this a prime matchup.
The Ravens are playing at home against a Giants team that’s struggling on offense. Lamar Jackson’s squad has been playing lockdown defense, and with Tommy DeVito under center for New York, expect the Ravens’ defense to feast. DeVito has been inconsistent and prone to turnovers, which could lead to a potential pick-six or a sack-fest for the Ravens defense. With their ability to shut down the run and create pressure, they are primed for a big Week 15 performance.
NFL DFS Week 15 Defense Picks
3. Miami Dolphins (FanDuel: $3,800; DraftKings: $2,500)
Data Deep Dive: Miami Dolphins defense ranks 3rd in the NFL with 15 total interceptions and 9th in sacks with 41 on the season, highlighting their ability to create turnovers and apply consistent pressure on the quarterback.
The Miami Dolphins have been sneaky good on defense this year, and they draw the Houston Texans in Week 15. With C.J. Stroud under center for Houston, there’s the potential for turnover-prone mistakes. Miami’s defense has a knack for creating pressure, and Stroud’s young career is not immune to missteps. With a game that could turn into a shootout, Miami will be in prime position to score on special teams or take advantage of a forced turnover, especially with their playmaking secondary. At their low price, the Dolphins are a high-upside pick for DFS players looking to maximize value.
NFL DFS Week 15 Defense Picks
4.New York Jets (FanDuel: $4,900; DraftKings: $3,000)
What We Know Mac Jones has thrown zero touchdown passes and five interceptions in his three starts for Jacksonville this season.
Sure, the Jets’ defense hasn’t exactly lit it up this season, but it’s still solid enough. And in Week 15, they’ve got the Jaguars, now led by Mac Jones, filling in for the injured Trevor Lawrence. Jones?Mac Jonesssss, well he’s tossed zero touchdown passes and five picks in three starts. Let’s just say, it’s a matchup the Jets’ D should be circling in red.
Closing Thoughts
Week 15 is where defenses make their money and DFS players cash in. The Cowboys bring the thunder with a pass rush that makes opposing quarterbacks wish they’d called in sick. The Ravens? They’ve got DeVito in their sights and a home crowd ready to roar. And the Dolphins? They’re quietly racking up picks and sacks like it’s a clearance sale. Even the Jets, with their ups and downs, have a golden ticket against a struggling Mac Jones. This is the week to invest smart, pick your playmakers, and watch your lineup soar!
NFL DFS LINEUP
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REMEMBER: These are lineups we use but feel free to pick and choose plays and make your own lineups. Don’t ALWAYS follow these as they don’t hit 100% of the time. We do use these but sometimes late scratches happen and it’s too late to update the lineup. Good luck and bring home the bacon.