Christian McCaffrey leads our NFL Week 10 RB Rankings as he and the San Francisco 49ers host the Los Angeles Chargers this week.
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Here are the Positional Rankings from FantasyTeamAdvisors.com for your NFL Week 10 RB Rankings
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NFL Week 10 RB Rankings
NFL Week 10 RB Rankings
| RK | PLAYER NAME | TEAM | OPP |
| 1 | Christian McCaffrey | SF | vs. LAC |
| 2 | Saquon Barkley | NYG | vs. HOU |
| 3 | Austin Ekeler | LAC | at SF |
| 4 | Derrick Henry | TEN | vs. DEN |
| 5 | Travis Etienne Jr. | JAC | at KC |
| 6 | Alvin Kamara | NO | at PIT |
| 7 | Josh Jacobs | LV | vs. IND |
| 8 | Nick Chubb | CLE | at MIA |
| 9 | Kenneth Walker III | SEA | at TB |
| 10 | Dameon Pierce | HOU | at NYG |
| 11 | Dalvin Cook | MIN | at BUF |
| 12 | Tony Pollard | DAL | at GB |
| 13 | Aaron Jones | GB | vs. DAL |
| 14 | Miles Sanders | PHI | vs. WAS |
| 15 | Leonard Fournette | TB | vs. SEA |
| 16 | Jonathan Taylor | IND | at LV |
| 17 | Jamaal Williams | DET | at CHI |
| 18 | David Montgomery | CHI | vs. DET |
| 19 | D'Andre Swift | DET | at CHI |
| 20 | James Conner | ARI | at LAR |
| 21 | Devin Singletary | BUF | vs. MIN |
| 22 | Najee Harris | PIT | vs. NO |
| 23 | Jeff Wilson Jr. | MIA | vs. CLE |
| 24 | Antonio Gibson | WAS | at PHI |
| 25 | Khalil Herbert | CHI | vs. DET |
| 26 | Kareem Hunt | CLE | at MIA |
| 27 | Raheem Mostert | MIA | vs. CLE |
| 28 | AJ Dillon | GB | vs. DAL |
| 29 | Rachaad White | TB | vs. SEA |
| 30 | Darrell Henderson Jr. | LAR | vs. ARI |
| 31 | Melvin Gordon III | DEN | at TEN |
| 32 | Ezekiel Elliott | DAL | at GB |
| 33 | Brian Robinson Jr. | WAS | at PHI |
| 34 | Clyde Edwards-Helaire | KC | vs. JAC |
| 35 | Isiah Pacheco | KC | vs. JAC |
| 36 | Dontrell Hilliard | TEN | vs. DEN |
| 37 | Latavius Murray | DEN | at TEN |
| 38 | Jerick McKinnon | KC | vs. JAC |
| 39 | Eno Benjamin | ARI | at LAR |
| 40 | Jaylen Warren | PIT | vs. NO |
| 41 | Kenneth Gainwell | PHI | vs. WAS |
| 42 | Alexander Mattison | MIN | at BUF |
| 43 | Nyheim Hines | BUF | vs. MIN |
| 44 | James Cook | BUF | vs. MIN |
| 45 | Rex Burkhead | HOU | at NYG |
| 46 | Chase Edmonds | DEN | at TEN |
| 47 | Cam Akers | LAR | vs. ARI |
| 48 | Travis Homer | SEA | at TB |
| 49 | JaMycal Hasty | JAC | at KC |
| 50 | Isaiah Spiller | LAC | at SF |
| 51 | Ameer Abdullah | LV | vs. IND |
| 52 | Matt Breida | NYG | vs. HOU |
| 53 | Boston Scott | PHI | vs. WAS |
| 54 | Elijah Mitchell | SF | vs. LAC |
| 55 | Dwayne Washington | NO | at PIT |
| 56 | Sony Michel | LAC | at SF |
| 57 | Brandon Bolden | LV | vs. IND |
| 58 | Kyren Williams | LAR | vs. ARI |
| 59 | Justin Jackson | DET | at CHI |
| 60 | Jordan Wilkins | IND | at LV |
| 61 | Zack Moss | IND | at LV |
| 62 | Keaontay Ingram | ARI | at LAR |
| 63 | Hassan Haskins | TEN | vs. DEN |
| 64 | DeeJay Dallas | SEA | at TB |
| 65 | Reggie Gilliam | BUF | vs. MIN |
| 66 | Kylin Hill | GB | vs. DAL |
| 67 | Kyle Juszczyk | SF | vs. LAC |
| 68 | C.J. Ham | MIN | at BUF |
| 69 | Zamir White | LV | vs. IND |
| 70 | Trestan Ebner | CHI | vs. DET |
| 71 | Dare Ogunbowale | HOU | at NYG |
| 72 | Alec Ingold | MIA | vs. CLE |
| 73 | Tyrion Davis-Price | SF | vs. LAC |
| 74 | Jordan Howard | NO | at PIT |
| 75 | Zander Horvath | LAC | at SF |
| 76 | Ronnie Rivers | LAR | vs. ARI |
| 77 | Ke'Shawn Vaughn | TB | vs. SEA |
| 78 | Jakob Johnson | LV | vs. IND |
| 79 | Snoop Conner | JAC | at KC |
| 80 | Michael Burton | KC | vs. JAC |
| 81 | D'Ernest Johnson | CLE | at MIA |
| 82 | Salvon Ahmed | MIA | vs. CLE |
| 83 | Gary Brightwell | NYG | vs. HOU |
| 84 | Derek Watt | PIT | vs. NO |
| 85 | Jonathan Williams | WAS | at PHI |
| 86 | Khari Blasingame | CHI | vs. DET |
| 87 | Malik Davis | DAL | at GB |
| 88 | Kene Nwangwu | MIN | at BUF |
| 89 | Qadree Ollison | DAL | at GB |
| 90 | Demetric Felton Jr. | CLE | at MIA |
| 91 | Patrick Taylor Jr. | GB | vs. DAL |
| 92 | Benny Snell Jr. | PIT | vs. NO |
| 93 | Corey Clement | ARI | at LAR |
| 94 | Duke Johnson Jr. | BUF | vs. MIN |
| 95 | Tevin Coleman | SF | vs. LAC |
| 96 | Tory Carter | TEN | vs. DEN |
| 97 | Larry Rountree III | LAC | at SF |
| 98 | Tony Jones Jr. | SEA | at TB |
| 99 | Jerome Ford | CLE | at MIA |
| 100 | Marlon Mack | DEN | at TEN |
| 101 | Darrynton Evans | CHI | vs. DET |
Our Other NFL Week 10 Rankings:
QB Rankings
WR Rankings
TE Rankings
DEF Rankings
NFL DFS LINEUP
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REMEMBER: These are lineups we use but feel free to pick and choose plays and make your own lineups. Don’t ALWAYS follow these as they don’t hit 100% of the time. We do use these but sometimes late scratches happen and it’s too late to update the lineup. Good luck and bring home the bacon.