This is where you’ll find the daily MLB Betting Odds breaking down pitchers, ballpark, runs, and all the sports betting info needing to win. Looking at the time of game, both pitchers, Implied Runs total or IRT, Opening Moneyline, Opening Over Unders, as well as Current Moneylines and Current Over/Unders.
MLB Vegas Odds — 4/15/26
| Time (ET) | Matchup | Favorite | Moneyline | Underdog | Moneyline |
|---|---|---|---|---|---|
| 12:35 PM | Arizona Diamondbacks @ Baltimore Orioles | Baltimore Orioles | -163 | Arizona Diamondbacks | +138 |
| 1:15 PM | Cleveland Guardians @ St. Louis Cardinals | St. Louis Cardinals | -105 | Cleveland Guardians | -105 |
| 1:40 PM | Boston Red Sox @ Minnesota Twins | Boston Red Sox | -136 | Minnesota Twins | +121 |
| 6:40 PM | Washington Nationals @ Pittsburgh Pirates | Pittsburgh Pirates | -180 | Washington Nationals | +150 |
| 6:40 PM | San Francisco Giants @ Cincinnati Reds | San Francisco Giants | -116 | Cincinnati Reds | +106 |
| 6:40 PM | Kansas City Royals @ Detroit Tigers | Detroit Tigers | -128 | Kansas City Royals | +117 |
| 6:40 PM | Chicago Cubs @ Philadelphia Phillies | Philadelphia Phillies | -143 | Chicago Cubs | +119 |
| 7:05 PM | Los Angeles Angels @ New York Yankees | New York Yankees | -226 | Los Angeles Angels | +184 |
| 7:15 PM | Miami Marlins @ Atlanta Braves | Atlanta Braves | -160 | Miami Marlins | +142 |
| 7:40 PM | Toronto Blue Jays @ Milwaukee Brewers | Milwaukee Brewers | -125 | Toronto Blue Jays | +105 |
| 7:40 PM | Tampa Bay Rays @ Chicago White Sox | Tampa Bay Rays | -110 | Chicago White Sox | +100 |
| 8:10 PM | Colorado Rockies @ Houston Astros | Houston Astros | -186 | Colorado Rockies | +153 |
| 9:40 PM | Texas Rangers @ Athletics | Texas Rangers | -125 | Athletics | +114 |
| 9:40 PM | Seattle Mariners @ San Diego Padres | Seattle Mariners | -114 | San Diego Padres | +104 |
| 10:10 PM | New York Mets @ Los Angeles Dodgers | Los Angeles Dodgers | -226 | New York Mets | +184 |
